The Kpandai District is one of the 261 Metropolitan, Municipal and District Assemblies (MMDAs) in Ghana, and forms part of the 16 MMDAs in the Northern Region.  

Kpandai district was curved out of the East Gonja district on 29th of February 2008 by an Act of Parliament through a Legislative Instrument 1885. It has Kpandai as its administrative capital.

The District is located at the south-eastern corner of the Northern Region of Ghana and lies between latitudes 8º N and 9.29º N and longitudes 0.29 º E and 1.26ºW. The district has a total land surface area of 1,132.9 Km Square.

It is bordered to the north by Nanumba South District, East Gonja Municipal to the west, Krachi West District to the south-west and Nkwanta North District to the east. 

The population of the District according to 2010 population and housing census stands at 108,816 with 54,997 males and 53,819 females.