The Amansie South District is one of the 261 Metropolitan, Municipal and District Assemblies (MMDAs) in Ghana, and forms part of the 43 of MMDAs in the Ashanti Region. 

The Amansie South District Assembly is carved out of the Amansie West District Assembly as one of the 38 newly created and upgraded districts Assemblies in 2018.

Created with LI 2325, the Amansie South District Assembly has its capital as Edubia.

It was inaugurated on March 15, 2018 alongside other 37 newly created districts.