The East Mamprusi Municipal is one of the 261 Metropolitan, Municipal and District Assemblies (MMDAs) in Ghana, and forms part of the 6 MMDAs in the North East Region.

The Municipality was established by Legislative Instrument (LI) 1776 (2004) with the capital located at Gambaga and it covers a land mass of 1,706.8 square kilometers. The Municipality is located in the north-eastern part of the Northern Region.

It is one of the oldest Municipalities in the Northern Region. Out of it, the West Mamprusi Municipal was carved in 1988. In 2004, the Bunkpurugu Nyankpanduri District was also created to promote developments. It therefore served as the parent District for West Mamprusi Municipal and Bunkpurugu Nyankpanduri Districts.

To the north, it shares boundaries with Talensi and Nabdam Districts, Bawku West and Garu Districts, all in the Upper East Region and to the east is the Bunkpurugu Nyankpanduri District. It is bordered in the west by the West Mamprusi Municipal and to the south by the Gushegu Municipal and Karaga District.

The population of the Municipality according to 2021 Population and Housing Census stands at  188,006 with 91,119 males and 96,887 females.