The Chereponi District is one of the 260 Metropolitan, Municipal and District Assemblies (MMDAs) in Ghana, and forms part of the 6 MMDAs in the Savannah Region and with its Administrative capital at Chereponi.

It is located between latitudes 10 °  10 ¹S and 10°N eastwards and longitude 10° 10¹ N and 10° 20¹ S northwards. The District has a total land area of approximately 1,080 sq. km. 

Politically, it is made up of one (1) Town and five (5) Area Councils. The Town Council is Chereponi while the Area Councils are Wenchiki, Tombo, Tambong, Nansoni and Wonjuga.

It shares boundaries with the following Districts; Gushegu Municipal to the west; Bunkpurugu Nyankpanduri District to the north, Saboba District to the south and The Republic of Togo to the east bordered by the River Oti.

The population of the District according to 2010 population and housing census stands at 53,394 with 26,206 males and 27,188 females.