The Ahafo Region is endowed with rich natural resources such as Gold, Diamonds, Timber etc. Gold deposit abounds in large quantities in the Mim, Ahafo, Kenyasi and Yamfo Areas. Newmont Gold Ghana Limited which is one of the biggest mining companies in the world, currently has their mining operations in the Kenyasi and Yamfo Areas in the Ahafo Region.

Ahafo Region being one of the forest belts in Ghana has a lot of forest reserves. Timber industry is the second highest employer in the Region. There are large and medium timber companies scattered across the Ahafo Region.

Notable among the timber companies in the Region are: 

• Ayum Forest Products Co. Ltd, 
• Exbo wood Co. Ltd, 
• Ocean-wood Co. Ltd, 
• Supremo-wood processing Co Ltd, all located at Mim in the Ahafo Region.

Ahafo Region is known to be the bread basket of Ghana. The soil type in the region supports the production of both food and cash crops. The region is known for its large cocoa and cashew productions.

The major agro-processing company in the region is

The Mim Cashew & Agric Products Co. LTD located at Mim, in the Ahafo Region