Bosomtwe District is located at the central portion of the Ashanti Region.

It lays within latitudes 6º 43’ north and longitudes 1º 46’ West Showing Bosomtwe District in the National and Regional context. 

The District is bounded on the North by Atwima Nwabiagya and Kumasi Metropolis and on the East by Ejisu- Juaben Municipal.

The southern section is bounded by Amansie West and East Districts. Kuntanase is the District Capital.

The population of the district according to the 2010 Population and Housing Census stands at 93,910 with 44,793 males 49,117 females.