Ejura-Sekyedumase District with Ejura as Capital was carved out of the former Sekyere and Offinso Districts and was thus created as a result of the implementation of the decentralized programmes on 29th November, 1988.

The district was established by a legislative instrument, PNDC L.I 1400, 1988.The district is located within longitudes 1˚5W and 1˚39’ W and latitudes 7˚9’ N and 7˚36’N. It has a large land size of about 1,782.2sq.km. (690.781sq.miles) and is the fifth largest district in Ashanti region’s 27 districts. It constitutes about 7.3% of the region’s total land area with about one third of its land area lying in the Afram Plains.

It is located in the Northern part of the Ashanti Region and is bounded in the north by Atebubu and Nkoranza districts (both in the Brong Ahafo region), on the west by Offinso district, on the East by Sekyere East district and the south by Sekyere West and Afigya Sekyere district.